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Azelain (Azelaic Acid): Active ingredient for acne and rosacea

Posted by Xeno Team on
Azelain

Azelaic acid

INCI: Azelaic Acid

Effect: reduces redness, has a decongestant effect, anti-inflammatory

Tolerability: good

Azelaic Acid is a carboxylic acid. It is neither one of the AHAs nor one of the BHAs. Azelain occurs naturally in wheat, rye and barley.

Azelaic acid effect

Azelaic acid is a potent active ingredient and is often used to treat severe acne and rosacea . Similar to Zinc PCA , it works against the acne-causing Propionibacterium acnes (P. Acnes). Dermatologists often prescribe up to 20% azelaic acid for acne.


Azelaic acid regulates the skin's oil production and ensures that the cells grow healthily and no longer become clogged as often. Because that is exactly what is often a problem with acne. Azelaic acid also lightens pimple marks , which is very beneficial for people with acne as the pimple marks can be treated at the same time.


In the treatment of rosacea, medicine uses the anti-inflammatory effect of azelaic acid. Up to 10-15% azelaic acid can be found in prescription creams such as Skinoren .


Unfortunately, due to its strong effects, azelaic acid also has side effects. Regular use can cause burning or drying out of the skin. However, when treating a skin disease, these side effects are usually accepted because the skin disease should not progress any further.

Rosacea is a skin condition that presents with redness Rosacea care: Avoid triggers and reduce redness
Woman with rosacea: Extensive redness on the cheeks and eyelids What is rosacea or couperose: treatment and experiences

Azelain alternative: mild azelain derivative

A milder derivative of azelaic acid is the azelaine derivative Potassium Azeloyl Diglycinate . This derivative does not have the side effects described above.

INCI: Potassium Azeloyl Diglycinate

Effect: reduces redness, has a decongestant effect, anti-inflammatory

Tolerability: very good

Potassium Azeloyl Diglycinate is suitable for milder forms of rosacea or if you are prone to “blemishes” and pimples .


Azelain Derivative moisturizes and is a great ingredient with anti-inflammatory and anti-acne effects without any side effects. It also has a lightening effect on pimple marks by inhibiting tyrosinase (a well-known enzyme required for the formation of melanin) and has a sebum-regulating effect. Potassium Azeloyl Diglycinate is a promising multifunctional ingredient that can be helpful for hyperpigmentation, mild acne or rosacea.

Products with mild Azelain derivative (Potassium Azeloyl Diglycinate)

Other ingredients suitable for rosacea

Horse Chestnut: Aesculus Hippocastanum Seed Extract
Squalane (Squalane): This skin-identical fat makes the skin supple

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